منابع مشابه
Neural Tube Defect and Folic Acid
نقص لوله عصبی یکی از ناهنجاریهای مادرزادی مهم و شایع می باشد که شیوع آن بیش از ۵/ ۴ در ۱۰۰۰ تولد زنده است. اتیولوژی و پاتوژنز بیماری هنوز ناشناخته است. مطالعات اخیر بر روی حیوانات نشان می دهد که این ناهنجاری ممکن است، ناشی از متابولیسم غیر طبیعی هموسیستئین باشد. در مطالعات اخیر مشخص شده است که پیشگیری از نقص لوله عصبی (NTD) بوسیله اسیدفولیک مؤثر می باشد.
متن کاملPrenatal Screening for Neural Tube Defect
Neural tube defect (NTD) is a serious congenital defect, but current methods for identifying NTD are limited. We used proteomic analysis of maternal serum to identify NTD-specific proteins whose levels differed between women with NTD fetuses (n = 50) and those with healthy fetuses (n = 40). Three NTD-specific protein peaks (8,130.6, 15,941.7, and 3,960.3 m/z) were identified using MALDI-TOF-mas...
متن کاملAbortion in neural tube defect fraternities.
Fraternities that include a fetus or person with a neural tube defect are remarkable for a high rate of recurrence of this type of malformation, about seven to eight times the overall rate (Record and McKeown, 1950; MacMahon, Pugh, and Ingalls, 1953; Carter, David, and Laurence,1968) and a higher than average rate of abortions (Murphy, 1940; Record and McKeown, 1950). Murphy (1940) found that a...
متن کاملRudimentary meningocele: remnant of a neural tube defect?
BACKGROUND Rudimentary meningocele, a malformation in which meningothelial elements are present in the skin and subcutaneous tissue, has been described in the past under a variety of different terms and has also been referred to as cutaneous meningioma. There has been debate as to whether rudimentary meningocele is an atretic form of meningocele or results from growth of meningeal cells displac...
متن کاملPrediction of neural tube defect using support vector machine.
OBJECTIVE To predict neural tube birth defect (NTD) using support vector machine (SVM). METHOD The dataset in the pilot area was divided into non overlaid training set and testing set. SVM was trained using the training set and the trained SVM was then used to predict the classification of NTD. RESULT NTD rate was predicted at village level in the pilot area. The accuracy of the prediction ...
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ژورنال
عنوان ژورنال: JBNC - JORNAL BRASILEIRO DE NEUROCIRURGIA
سال: 2018
ISSN: 2446-6786
DOI: 10.22290/jbnc.v28i1.1635